Publications

The scientific production of the Center has grown over time since its establishment. In the last 5 years the CGR’s researchers have published 74 papers with a total IF of 763.973 and an average IF of 9.017

Usefulness and Limitations of Comprehensive Characterization of mRNA Splicing Profiles in the Definition of the Clinical Relevance of BRCA1/2 Variants of Uncertain Significance.

Gelli E, Colombo M, Pinto AM, De Vecchi G, Foglia C, Amitrano S, Morbidoni V, Imperatore V, Manoukian S, Baldassarri M, Lo Rizzo C, Catania L, Frullanti E, Tagliafico E, Cortesi L, Spaggiari F, Mencarelli MA, Trevisson E, Radice P, Renieri A, Ariani F. Cancers (Basel). 2019 Mar 1;11(3). pii: E295. doi: 10.3390/cancers11030295. PMID: 30832263 [PubMed] Free Article

Gene expression profiles of human granulosa cells treated with bioequivalent doses of corifollitropin alfa (CFA) or recombinant human follicle-stimulating hormone (recFSH).

Sacchi S, Tenedini E, Tondelli D, Parenti S, Tagliasacchi D, Xella S, Marsella T, Tagliafico E, La Marca A. Gynecol Endocrinol. 2019 Feb 20:1-5. doi: 10.1080/09513590.2019.1576611. [Epub ahead of print] PMID: 30784329 [PubMed – as supplied by publisher]

Magnesium Is a Key Regulator of the Balance between Osteoclast and Osteoblast Differentiation in the Presence of Vitamin D₃.

Mammoli F, Castiglioni S, Parenti S, Cappadone C, Farruggia G, Iotti S, Davalli P, Maier JAM, Grande A, Frassineti C. Int J Mol Sci. 2019 Jan 17;20(2). pii: E385. doi: 10.3390/ijms20020385. PMID: 30658432 [PubMed – in process] Free PMC Article

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Théry C, Witwer KW, et al. J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018. PMID: 30637094 [PubMed] Free PMC Article

Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach.

Casarini L, Riccetti L, Limoncella S, Lazzaretti C, Barbagallo F, Pacifico S, Guerrini R, Tagliavini S, Trenti T, Simoni M, Sola M, Di Rocco G. Biochemistry. 2019 Feb 12;58(6):799-808. doi: 10.1021/acs.biochem.8b01073. Epub 2018 Dec 21. PMID: 30532959 [PubMed – in process]

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.

Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, Sartoris S, Solito S, Mandruzzato S, Vascotto F, Hippen KL, Mondanelli G, Grohmann U, Piro G, Carbone C, Melisi D, Lawlor RT, Scarpa A, Lamolinara A, Iezzi M, Fassan M, Bicciato S, Blazar BR, Sahin U, Murray PJ, Bronte V. Nat Commun. 2018 Dec 5;9(1):5193. doi: 10.1038/s41467-018-07654-4. PMID: 30518925 [PubMed – indexed for MEDLINE] Free PMC Article

Workload measurement for molecular genetics laboratory: A survey study.

Tagliafico E, Bernardis I, Grasso M, D’Apice MR, Lapucci C, Botta A, Giachino DF, Marinelli M, Primignani P, Russo S, Sani I, Seia M, Fini S, Rimessi P, Tenedini E, Ravani A, Genuardi M, Ferlini A; Molecular Genetics Working Group of the Italian Society of Human Genetics, SIGU. PLoS One. 2018 Nov 27;13(11):e0206855. doi: 10.1371/journal.pone.0206855. eCollection 2018. PMID: 30481188 [PubMed – in process] Free PMC Article

Enzymatic Inactivation of Oxysterols in Breast Tumor Cells Constraints Metastasis Formation by Reprogramming the Metastatic Lung Microenvironment.

Moresco MA, Raccosta L, Corna G, Maggioni D, Soncini M, Bicciato S, Doglioni C, Russo V. Front Immunol. 2018 Oct 2;9:2251. doi: 10.3389/fimmu.2018.02251. eCollection 2018. PMID: 30333826 [PubMed – in process] Free PMC Article

Loss of expression of μ-protocadherin and protocadherin-24 in sporadic and hereditary nonpolyposis colorectal cancers.

Losi L, Lancellotti C, Parenti S, Scurani L, Zanocco-Marani T, Buffoli F, Grassia R, Ferrari S, Grande A. Hum Pathol. 2019 Feb;84:299-308. doi: 10.1016/j.humpath.2018.09.019. Epub 2018 Oct 5. PMID: 30296522 [PubMed – in process]

Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis.

Rossi C, Zini R, Rontauroli S, Ruberti S, Prudente Z, Barbieri G, Bianchi E, Salati S, Genovese E, Bartalucci N, Guglielmelli P, Tagliafico E, Rosti V, Barosi G, Vannucchi AM, Manfredini R; AGIMM (AIRC-Gruppo Italiano Malattie Mieloproliferative) investigators. Mol Oncol. 2018 Dec;12(12):2102-2123. doi: 10.1002/1878-0261.12387. Epub 2018 Nov 16. PMID: 30259659 [PubMed – in process] Free PMC Article

Author Correction: MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.

Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A. Nat Commun. 2018 Sep 20;9(1):3921. doi: 10.1038/s41467-018-06480-y. PMID: 30237396 [PubMed] Free PMC Article

Genomic alterations at the basis of treatment resistance in metastatic breast cancer: clinical applications.

Toss A, Piacentini F, Cortesi L, Artuso L, Bernardis I, Parenti S, Tenedini E, Ficarra G, Maiorana A, Iannone A, Omarini C, Moscetti L, Cristofanilli M, Federico M, Tagliafico E.
Oncotarget. 2018 Aug 3;9(60):31606-31619. doi: 10.18632/oncotarget.25810. eCollection 2018 Aug 3.
PMID: 30167082 [PubMed] Free PMC Article

KLF4 Mediates the Effect of 5-ASA on the β-Catenin Pathway in Colon Cancer Cells.

Parenti S, Montorsi L, Fantini S, Mammoli F, Gemelli C, Atene CG, Losi L, Frassineti C, Calabretta B, Tagliafico E, Ferrari S, Zanocco-Marani T, Grande A. Cancer Prev Res (Phila). 2018 Aug;11(8):503-510. doi: 10.1158/1940-6207.CAPR-17-0382. Epub 2018 May 24. PMID: 29794245 [PubMed – in process]

Transcriptional profiling of human bronchial epithelial cell BEAS-2B exposed to diesel and biomass ultrafine particles. Grilli A, Bengalli R, Longhin E, Capasso L, Proverbio MC, Forcato M, Bicciato S, Gualtieri M, Battaglia C, Camatini M. BMC Genomics. 2018 Apr 27;19(1):302. doi: 10.1186/s12864-018-4679-9. PMID: 29703138 [PubMed – indexed for MEDLINE] Free PMC Article

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Nicolas A, Kenna KP, et al.. Neuron. 2018 Mar 21;97(6):1268-1283.e6. doi: 10.1016/j.neuron.2018.02.027. PMID: 29566793 [PubMed – in process]

A gene expression signature of Retinoblastoma loss-of-function predicts resistance to neoadjuvant chemotherapy in ER-positive/HER2-positive breast cancer patients.

Risi E, Grilli A, Migliaccio I, Biagioni C, McCartney A, Guarducci C, Bonechi M, Benelli M, Vitale S, Biganzoli L, Bicciato S, Di Leo A, Malorni L. Breast Cancer Res Treat. 2018 Jul;170(2):329-341. doi: 10.1007/s10549-018-4766-2. Epub 2018 Mar 22. PMID: 29564743 [PubMed – indexed for MEDLINE]

Bimodal CD40/Fas-Dependent Crosstalk between iNKT Cells and Tumor-Associated Macrophages Impairs Prostate Cancer Progression.

Cortesi F, Delfanti G, Grilli A, Calcinotto A, Gorini F, Pucci F, Lucianò R, Grioni M, Recchia A, Benigni F, Briganti A, Salonia A, De Palma M, Bicciato S, Doglioni C, Bellone M, Casorati G, Dellabona P. Cell Rep. 2018 Mar 13;22(11):3006-3020. doi: 10.1016/j.celrep.2018.02.058. PMID: 29539427 [PubMed – in process] Free Article

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.

Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A. Nat Commun. 2018 Mar 9;9(1):1024. doi: 10.1038/s41467-018-03264-2. Erratum in:  Nat Commun. 2018 Sep 20;9(1):3921. PMID: 29523784 [PubMed – indexed for MEDLINE] Free PMC Article

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z. Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31. PMID: 29503198 [PubMed – in process] Free Article

Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes.

Martinelli S, Krumbach OHF, Pantaleoni F, Coppola S, Amin E, Pannone L, Nouri K, Farina L, Dvorsky R, Lepri F, Buchholzer M, Konopatzki R, Walsh L, Payne K, Pierpont ME, Vergano SS, Langley KG, Larsen D, Farwell KD, Tang S, Mroske C, Gallotta I, Di Schiavi E, Della Monica M, Lugli L, Rossi C, Seri M, Cocchi G, Henderson L, Baskin B, Alders M, Mendoza-Londono R, Dupuis L, Nickerson DA, Chong JX; University of Washington Center for Mendelian Genomics, Meeks N, Brown K, Causey T, Cho MT, Demuth S, Digilio MC, Gelb BD, Bamshad MJ, Zenker M, Ahmadian MR, Hennekam RC, Tartaglia M, Mirzaa GM. Am J Hum Genet. 2018 Feb 1;102(2):309-320. doi: 10.1016/j.ajhg.2017.12.015. Epub 2018 Jan 25. PMID: 29394990 [PubMed – in process] Free PMC Article

Calreticulin affects hematopoietic stem/progenitor cell fate by impacting erythroid and megakaryocytic differentiation.

Salati S, Prudente Z, Genovese E, Pennucci V, Rontauroli S, Bartalucci N, Mannarelli C, Ruberti S, Zini R, Rossi C, Bianchi E, Guglielmelli P, Tagliafico E, Vannucchi AM, Manfredini R. Stem Cells Dev. 2017 Dec 19. doi: 10.1089/scd.2017.0137. [Epub ahead of print] PMID: 29258411 [PubMed – as supplied by publisher]

CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles.

Zini R, Guglielmelli P, Pietra D, Rumi E, Rossi C, Rontauroli S, Genovese E, Fanelli T, Calabresi L, Bianchi E, Salati S, Cazzola M, Tagliafico E, Vannucchi AM, Manfredini R; AGIMM (AIRC Gruppo Italiano Malattie Mieloproliferative) investigators. Blood Cancer J. 2017 Dec 8;7(12):638. doi: 10.1038/s41408-017-0010-2. PMID: 29217833 [PubMed – indexed for MEDLINE] Free PMC Article

Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients.

Ruberti S, Bianchi E, Guglielmelli P, Rontauroli S, Barbieri G, Tavernari L, Fanelli T, Norfo R, Pennucci V, Fattori GC, Mannarelli C, Bartalucci N, Mora B, Elli L, Avanzini MA, Rossi C, Salmoiraghi S, Zini R, Salati S, Prudente Z, Rosti V, Passamonti F, Rambaldi A, Ferrari S, Tagliafico E, Vannucchi AM, Manfredini R. Leukemia. 2018 Feb;32(2):438-449. doi: 10.1038/leu.2017.220. Epub 2017 Jul 12. PMID: 28745329 [PubMed – indexed for MEDLINE] Free PMC Article

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.

Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G. EMBO Rep. 2017 Aug;18(8):1331-1351. doi: 10.15252/embr.201643370. Epub 2017 Jun 26. PMID: 28652379 [PubMed – indexed for MEDLINE] Free PMC Article

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions.

Romano O, Cifola I, Poletti V, Severgnini M, Peano C, De Bellis G, Mavilio F, Miccio A. J Vis Exp. 2017 May 28;(123). doi: 10.3791/55919. PMID: 28605390 [PubMed – indexed for MEDLINE]

Comparison of computational methods for Hi-C data analysis.

Forcato M, Nicoletti C, Pal K, Livi CM, Ferrari F, Bicciato S. Nat Methods. 2017 Jul;14(7):679-685. doi: 10.1038/nmeth.4325. Epub 2017 Jun 12. PMID: 28604721 [PubMed – indexed for MEDLINE] Free PMC Article

uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells.

Laurenzana A, Chillà A, Luciani C, Peppicelli S, Biagioni A, Bianchini F, Tenedini E, Torre E, Mocali A, Calorini L, Margheri F, Fibbi G, Del Rosso M. Int J Cancer. 2017 Sep 15;141(6):1190-1200. doi: 10.1002/ijc.30817. Epub 2017 Jun 21. PMID: 28577299 [PubMed – indexed for MEDLINE] Free Article

Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells.

Salati S, Salvestrini V, Carretta C, Genovese E, Rontauroli S, Zini R, Rossi C, Ruberti S, Bianchi E, Barbieri G, Curti A, Castagnetti F, Gugliotta G, Rosti G, Bergamaschi M, Tafuri A, Tagliafico E, Lemoli R, Manfredini R. Oncotarget. 2017 Jul 25;8(30):49451-49469. doi: 10.18632/oncotarget.17706. PMID: 28533480 [PubMed – indexed for MEDLINE] Free PMC Article

The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta.

Gioia R, Tonelli F, Ceppi I, Biggiogera M, Leikin S, Fisher S, Tenedini E, Yorgan TA, Schinke T, Tian K, Schwartz JM, Forte F, Wagener R, Villani S, Rossi A, Forlino A. Hum Mol Genet. 2017 Aug 1;26(15):2897-2911. doi: 10.1093/hmg/ddx171. PMID: 28475764 [PubMed – indexed for MEDLINE] Free PMC Article

WoPPER: Web server for Position Related data analysis of gene Expression in Prokaryotes.

Puccio S, Grillo G, Licciulli F, Severgnini M, Liuni S, Bicciato S, De Bellis G, Ferrari F, Peano C. Nucleic Acids Res. 2017 Jul 3;45(W1):W109-W115. doi: 10.1093/nar/gkx329. PMID: 28460063 [PubMed – in process] Free PMC Article

Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors.

Riccetti L, Yvinec R, Klett D, Gallay N, Combarnous Y, Reiter E, Simoni M, Casarini L, Ayoub MA. Sci Rep. 2017 Apr 19;7(1):940. doi: 10.1038/s41598-017-01078-8. PMID: 28424471 [PubMed – indexed for MEDLINE] Free PMC Article

Unravelling the Complexity of Inherited Retinal Dystrophies Molecular Testing: Added Value of Targeted Next-Generation Sequencing.

Bernardis I, Chiesi L, Tenedini E, Artuso L, Percesepe A, Artusi V, Simone ML, Manfredini R, Camparini M, Rinaldi C, Ciardella A, Graziano C, Balducci N, Tranchina A, Cavallini GM, Pietrangelo A, Marigo V, Tagliafico E. Biomed Res Int. 2016;2016:6341870. doi: 10.1155/2016/6341870. Epub 2016 Dec 29. PMID: 28127548 [PubMed – indexed for MEDLINE] Free PMC Article

Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis.

Bianchi E, Ruberti S, Rontauroli S, Guglielmelli P, Salati S, Rossi C, Zini R, Tagliafico E, Vannucchi AM, Manfredini R. Int J Mol Sci. 2017 Jan 13;18(1). pii: E145. doi: 10.3390/ijms18010145. PMID: 28098757 [PubMed – indexed for MEDLINE] Free PMC Article

Identification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants.

Capri M, Olivieri F, Lanzarini C, Remondini D, Borelli V, Lazzarini R, Graciotti L, Albertini MC, Bellavista E, Santoro A, Biondi F, Tagliafico E, Tenedini E, Morsiani C, Pizza G, Vasuri F, D’Errico A, Dazzi A, Pellegrini S, Magenta A, D’Agostino M, Capogrossi MC, Cescon M, Rippo MR, Procopio AD, Franceschi C, Grazi GL. Aging Cell. 2017 Apr;16(2):262-272. doi: 10.1111/acel.12549. Epub 2016 Dec 20. PMID: 27995756 [PubMed – indexed for MEDLINE] Free PMC Article

Skeletal muscle characteristics are preserved in hTERT/cdk4 human myogenic cell lines.

Thorley M, Duguez S, Mazza EMC, Valsoni S, Bigot A, Mamchaoui K, Harmon B, Voit T, Mouly V, Duddy W. Skelet Muscle. 2016 Dec 8;6(1):43. doi: 10.1186/s13395-016-0115-5. PMID: 27931240 [PubMed – indexed for MEDLINE] Free PMC Article

MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.

Lo Sardo F, Forcato M, Sacconi A, Capaci V, Zanconato F, Di Agostino S, Del Sal G, Pandolfi PP, Strano S, Bicciato S, Blandino G.
Carcinogenesis. 2017 Jan;38(1):64-75. doi: 10.1093/carcin/bgw110. Epub 2016 Oct 17. PMID: 27797825 [PubMed – indexed for MEDLINE] Free PMC Article

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.

Panciera T, Azzolin L, Fujimura A, Di Biagio D, Frasson C, Bresolin S, Soligo S, Basso G, Bicciato S, Rosato A, Cordenonsi M, Piccolo S. Cell Stem Cell. 2016 Dec 1;19(6):725-737. doi: 10.1016/j.stem.2016.08.009. Epub 2016 Sep 15. PMID: 27641305 [PubMed – indexed for MEDLINE] Free PMC Article

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.

Marigo I, Zilio S, Desantis G, Mlecnik B, Agnellini AHR, Ugel S, Sasso MS, Qualls JE, Kratochvill F, Zanovello P, Molon B, Ries CH, Runza V, Hoves S, Bilocq AM, Bindea G, Mazza EMC, Bicciato S, Galon J, Murray PJ, Bronte V.Cancer Cell. 2016 Sep 12;30(3):377-390. doi: 10.1016/j.ccell.2016.08.004. Erratum in: Cancer Cell. 2016 Oct 10;30(4):651. PMID: 27622331 [PubMed – indexed for MEDLINE] Free PMC Article

lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome.

Ronchetti D, Manzoni M, Agnelli L, Vinci C, Fabris S, Cutrona G, Matis S, Colombo M, Galletti S, Taiana E, Recchia AG, Bossio S, Gentile M, Musolino C, Di Raimondo F, Grilli A, Bicciato S, Cortelezzi A, Tassone P, Morabito F, Ferrarini M, Neri A. Blood Cancer J. 2016 Sep 9;6(9):e468. doi: 10.1038/bcj.2016.77. PMID: 27611921 [PubMed – indexed for MEDLINE] Free PMC Article

A comparative transcriptomic analysis of astrocytes differentiation from human neural progenitor cells.

Magistri M, Khoury N, Mazza EM, Velmeshev D, Lee JK, Bicciato S, Tsoulfas P, Faghihi MA. Eur J Neurosci. 2016 Nov;44(10):2858-2870. doi: 10.1111/ejn.13382. Epub 2016 Sep 25. PMID: 27564458 [PubMed – indexed for MEDLINE] Free PMC Article

β-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line.

Casarini L, Reiter E, Simoni M. Mol Cell Endocrinol. 2016 Dec 5;437:11-21. doi: 10.1016/j.mce.2016.08.005. Epub 2016 Aug 5. PMID: 27502035 [PubMed – indexed for MEDLINE]

MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity.

Moretti I, Ciciliot S, Dyar KA, Abraham R, Murgia M, Agatea L, Akimoto T, Bicciato S, Forcato M, Pierre P, Uhlenhaut NH, Rigby PW, Carvajal JJ, Blaauw B, Calabria E, Schiaffino S. Nat Commun. 2016 Aug 3;7:12397. doi: 10.1038/ncomms12397. PMID: 27484840 [PubMed – indexed for MEDLINE] Free PMC Article

Integrated evaluation of PAM50 subtypes and immune modulation of pCR in HER2-positive breast cancer patients treated with chemotherapy and HER2-targeted agents in the CherLOB trial.

Dieci MV, Prat A, Tagliafico E, Paré L, Ficarra G, Bisagni G, Piacentini F, Generali DG, Conte P, Guarneri V. Ann Oncol. 2016 Oct;27(10):1867-73. doi: 10.1093/annonc/mdw262. Epub 2016 Aug 2. PMID: 27484801 [PubMed – indexed for MEDLINE]

Copy number variation at the HvCBF4-HvCBF2 genomic segment is a major component of frost resistance in barley.

Francia E, Morcia C, Pasquariello M, Mazzamurro V, Milc JA, Rizza F, Terzi V, Pecchioni N. Plant Mol Biol. 2016 Sep;92(1-2):161-75. doi: 10.1007/s11103-016-0505-4. Epub 2016 Jun 23. PMID: 27338258 [PubMed – indexed for MEDLINE]

Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes.

Montorsi L, Parenti S, Losi L, Ferrarini F, Gemelli C, Rossi A, Manco G, Ferrari S, Calabretta B, Tagliafico E, Zanocco-Marani T, Grande A. Cell Death Dis. 2016 Jun 16;7:e2263. doi: 10.1038/cddis.2016.163. PMID: 27310872 [PubMed – indexed for MEDLINE] Free PMC Article

No Identical “Mesenchymal Stem Cells” at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels.

Sacchetti B, Funari A, Remoli C, Giannicola G, Kogler G, Liedtke S, Cossu G, Serafini M, Sampaolesi M, Tagliafico E, Tenedini E, Saggio I, Robey PG, Riminucci M, Bianco P. Stem Cell Reports. 2016 Jun 14;6(6):897-913. doi: 10.1016/j.stemcr.2016.05.011. PMID: 27304917 [PubMed – indexed for MEDLINE] Free PMC Article

Epidemiology and clinical relevance of mutations in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 359 patients of the AGIMM group.

Rotunno G, Pacilli A, Artusi V, Rumi E, Maffioli M, Delaini F, Brogi G, Fanelli T, Pancrazzi A, Pietra D, Bernardis I, Belotti C, Pieri L, Sant’Antonio E, Salmoiraghi S, Cilloni D, Rambaldi A, Passamonti F, Barbui T, Manfredini R, Cazzola M, Tagliafico E, Vannucchi AM, Guglielmelli P. Am J Hematol. 2016 Jul;91(7):681-6. doi: 10.1002/ajh.24377. Epub 2016 May 11. PMID: 27037840 [PubMed – indexed for MEDLINE] Free Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen wt al. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. No abstract available. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban]PMID: 26799652 [PubMed – indexed for MEDLINE] Free PMC Article

Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters.

Marinello J, Bertoncini S, Aloisi I, Cristini A, Malagoli Tagliazucchi G, Forcato M, Sordet O, Capranico G. PLoS One. 2016 Jan 19;11(1):e0147053. doi: 10.1371/journal.pone.0147053. eCollection 2016. PMID: 26784695 [PubMed – indexed for MEDLINE] Free PMC Article

The calcineurin-NFAT pathway controls activity-dependent circadian gene expression in slow skeletal muscle.

Dyar KA, Ciciliot S, Tagliazucchi GM, Pallafacchina G, Tothova J, Argentini C, Agatea L, Abraham R, Ahdesmäki M, Forcato M, Bicciato S, Schiaffino S, Blaauw B. Mol Metab. 2015 Sep 25;4(11):823-33. doi: 10.1016/j.molmet.2015.09.004. eCollection 2015 Nov. PMID: 26629406 [PubMed] Free PMC Article

Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.

Salati S, Zini R, Nuzzo S, Guglielmelli P, Pennucci V, Prudente Z, Ruberti S, Rontauroli S, Norfo R, Bianchi E, Bogani C, Rotunno G, Fanelli T, Mannarelli C, Rosti V, Salmoiraghi S, Pietra D, Ferrari S, Barosi G, Rambaldi A, Cazzola M, Bicciato S, Tagliafico E, Vannucchi AM, Manfredini R; AGIMM (AIRC Gruppo Italiano Malattie Mieloproliferative) investigators. Int J Cancer. 2016 Apr 1;138(7):1657-69. doi: 10.1002/ijc.29920. Epub 2015 Nov 25. PMID: 26547506 [PubMed – indexed for MEDLINE] Free Article

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs.

Choi J, Lee S, Mallard W, Clement K, Tagliazucchi GM, Lim H, Choi IY, Ferrari F, Tsankov AM, Pop R, Lee G, Rinn JL, Meissner A, Park PJ, Hochedlinger K. Nat Biotechnol. 2015 Nov;33(11):1173-81. doi: 10.1038/nbt.3388. Epub 2015 Oct 26. PMID: 26501951 [PubMed – indexed for MEDLINE] Free PMC Article

APTANI: a computational tool to select aptamers through sequence-structure motif analysis of HT-SELEX data.

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